Antidiuretic hormone replacement resolves the symptoms of increased thirst and urination seen in ID sufferers. When a tumor is determined to be the culprit of DI, surgery to remove it may be the only alternative; however, hormone replacement therapy may also be necessary later. In general, disorders and diseases of the pituitary gland are quite common diseases, especially those resulting from tumors, since at least one in five people can develop one, although they are often mostly benign; however, despite ongoing research, the cause of these remains unknown. Most of them occur without any genetic bias and very few are hereditary, but intensive research has not yet discovered why they are so common. In the past, the incidence of pituitary tumors was not included in statistics collected by state tumor registries and the National Cancer Institute, but since 2002 it has been legally required that hospitals, clinics, and independent physicians report any incidence rates of pituitary tumors when they collect data for tumor registry. This is indeed a very important step on the path towards more thorough discovery of the conditions that lead to the appearance of these cancerous growths, because the pituitary gland is one of the most vital glands
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